Access evidence-based insights
Use scientist-curated knowledge base to support variant interpretation and reporting.
navify® Mutation Profiler
Simplifying NGS research and clinical interpretation.
This page at a glance
- Product description
- A cloud-based tertiary analysis software that delivers high-quality interpretive results by integrating comprehensive case and variant statistics, giving labs with a platform for reliable data management and streamlined decision-making.
- Primary value
- It supports labs in interpreting genomic variants and assessing their significance with evidence-based content to support precision oncology decision making and workflows.
- Intuitive workflow
- Variant interpretation
- Customizable reports
- Workflow support
- Trial information
- Evidence-based knowledge repository
Overview
Support variant interpretation and reporting with a NGS reporting solution
navify Mutation Profiler, an NGS reporting solution, provides access to a scientist-curated, evidence-based knowledge repository and supports variant interpretation and reporting with region specific content, guidelines and trial information.
Support workflows
Streamline NGS analysis and reporting with an intuitive step-by-step workflow.
Interpret variant combinations
Understand implications of variants in isolation and combination.
Standardize genomic reporting
Create comprehensive genomic insights reports with regional specific content and guidelines.
Workflow designed for NGS reporting
navify Mutation Profiler supports the laboratory workflow from case creation through report delivery. Users can review variants, reclassify findings, revise therapies, select from trials and write case-level summaries. The solution provides access to regional guidelines, approvals and content to support interpretation and reporting workflows.
Review and prioritize variants
Review variants with supporting evidence and understand implications of individual variants and variant combinations.
Customize genomic reports
Configure reports with relevant findings, selected therapies, trials and case-level summaries.
Stay current and compliant
Access updated medical guidelines, regulatory approvals and region-specific variant tier classifications.
Integrate information
Connect information sources to support interpretation and multidisciplinary workflows.
Leverage a curated knowledge base
Access a scientist-curated, evidence-based knowledge repository with content covering genes, variants, structural variants, biomarker profiles and genomic signatures across major solid tumor types and hematologic malignancies. It supports interpretation of complex genomic data with curated biomarker/disease associations.
Extensive genomic content across cancer types and biomarkers
The knowledge base provides broad coverage across dozens of solid tumor types and hematologic malignancies. It encompasses tens of thousands of curated variants, genes, biomarker profiles and structural variants alongside complex genomic signatures, enabling multi-faceted biomarker-to-disease matching across extensive datasets.
Support informed genomic decision-making with confidence
navify Mutation Profiler helps laboratories interpret complex genomic data by providing access to evidence-based content, streamlined workflows and reporting tools. It supports users in assessing significance, reviewing relevant information and preparing genomic reports for multidisciplinary teams. NGS tumor profiling enables identification of mutations that may guide therapeutic decisions and potentially improve the outcome of patients with cancer.
Understand the significance of variants
Review variants in isolation and combination with supporting evidence, regional guidelines and variant tier classifications. Access updated content and approvals to support interpretation and informed decision-making.
Streamline genomic analysis reporting
Use an intuitive workflow designed for the lab to review variants, customize reports and support tertiary analysis. The solution helps simplify genomic reporting processes and supports efficient case review.
Support collaboration across care teams
Connect relevant molecular and case information to support multidisciplinary workflows and collaborative decision-making.
Increase efficiency in report curation
navify Mutation Profiler supports streamlined report curation workflows compared with manual curation.
75%time saved on report curation
compared with manual curation.1
Frequently asked questions about navify Mutation Profiler
If you don’t find answers to your questions here, we’re happy to provide more information and discuss your needs in detail.
Roche Diagnostics
At Roche Diagnostics, we understand the need to go beyond our products and see the bigger picture, creating a world where product and services come together. Roche Service Solutions refers to our service offering and encompasses our full service portfolio. Our total solution package means we can provide you with the personalised mix of products and services you need. Our digital services enable you to quickly connect with us and help make your life more manageable.
- Yaung SJ, Pek A. From information overload to actionable insights: digital solutions for interpreting cancer variants from genomic testing. JMP. 2021;2(4):312–318. [DOI: 10.3390/jmp2040027].
- Not every digital product is available in all markets. The use of any third-party app is subject to a separate license agreement with the respective third-party app developer. Roche gives no warranties (express or implied) with regard to any third-party app. Third-party apps might not be available in your country. This website and its content may be accessible worldwide, Roche assumes no liability with regard to the access to the information, which may not be compatible with legislations or regulations in force in your country.
- *navify Mutation Profiler is CE-IVD. In the US, navify Mutation Profiler is Research Use Only (RUO). Not for use in diagnostic procedures or decisions. This information is intended for EU audiences only.
- MC--15707